Microbial Pathogenesis and Virulence
Although the overwhelming majority of microorganism area unit harmless or useful, quite an few microorganism area unit bacteria. Bacterial microorganism area unit microorganism that cause microorganism infection. one amongst the microorganism unwellnesss with highest disease burden is T.B caused by the microorganism tubercle bacillus, that kills concerning a pair of million individuals a year, largely in geographical region. Bacteria microorganism contribute to different globally necessary diseases, like respiratory disease and food borne diseases. Bacteria microorganism conjointly cause infections like tetanus, infectious disease, diphtheria, syphilis, and infectious disease.
In sure infections tissue injury results from the cytotoxic mediators discharged by bodily fluid cells instead of from microorganism toxins.
Bacterial virulence factors is also encoded on body, plasmid, transposon, or temperate virus polymer; virulence issue genes on transposons or temperate virus DNA might integrate into the microorganism body.
The following are types of virulence factors:
· invade the host
· evade host defenses.
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